MEX - VVI

C$ 337 Find Cheap Flights from Mexico City to Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Mexico City to Santa Cruz de la Sierra departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Santa Cruz de la Sierra, as well as popular online travel agencies
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Cheap Flights from Mexico City to Santa Cruz de la Sierra (MEX-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Mexico City to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Mexico City to Santa Cruz de la Sierra

Sun, 5 Oct - Sun, 12 Oct
 Logo
3:10 p.m. - 4:35 a.m.MEX-VVI
11h 25m1 stop
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5:20 a.m. - 11:20 a.m.VVI-MEX
32h 00m2 stops
C$ 790
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Mon, 13 Oct - Wed, 22 Oct
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12:15 a.m. - 4:35 a.m.MEX-VVI
26h 20m2 stops
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5:20 a.m. - 9:40 a.m.VVI-MEX
30h 20m2 stops
C$ 803
Find Deal
Wed, 3 Sep - Tue, 9 Sep
Copa Airlines Logo
1:05 p.m. - 3:36 a.m.MEX-VVI
12h 31m1 stop
Copa Airlines Logo
12:15 p.m. - 10:05 p.m.VVI-MEX
11h 50m1 stop
C$ 810Copa Airlines
Find Deal
Mon, 5 Jan - Wed, 14 Jan
Copa Airlines Logo
1:20 a.m. - 10:50 p.m.MEX-VVI
19h 30m1 stop
Copa Airlines Logo
1:15 a.m. - 7:20 p.m.VVI-MEX
20h 05m1 stop
C$ 827Copa Airlines
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Wed, 1 Oct - Tue, 14 Oct
Copa Airlines Logo
2:00 a.m. - 10:17 p.m.MEX-VVI
18h 17m1 stop
Copa Airlines Logo
11:59 a.m. - 12:15 a.m.VVI-MEX
14h 16m1 stop
C$ 843Copa Airlines
Find Deal
Thu, 30 Oct - Fri, 27 Feb
Copa Airlines Logo
2:00 a.m. - 10:40 p.m.MEX-VVI
18h 40m1 stop
Copa Airlines Logo
1:15 a.m. - 7:20 p.m.VVI-MEX
20h 05m1 stop
C$ 857Copa Airlines
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Thu, 2 Oct - Tue, 14 Oct
Copa Airlines Logo
9:50 a.m. - 10:17 p.m.MEX-VVI
10h 27m1 stop
Copa Airlines Logo
11:59 a.m. - 1:00 a.m.VVI-MEX
15h 01m1 stop
C$ 861Copa Airlines
Find Deal
Mon, 5 Jan - Wed, 14 Jan
Copa Airlines Logo
1:20 a.m. - 10:50 p.m.MEX-VVI
19h 30m1 stop
Copa Airlines Logo
1:15 a.m. - 7:20 p.m.VVI-MEX
20h 05m1 stop
C$ 865Copa Airlines
Find Deal
Sat, 4 Oct - Sun, 12 Oct
 Logo
12:15 a.m. - 4:35 a.m.MEX-VVI
26h 20m2 stops
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5:20 a.m. - 10:35 a.m.VVI-MEX
31h 15m2 stops
C$ 872
Find Deal
Thu, 30 Oct - Sat, 28 Feb
Copa Airlines Logo
2:00 a.m. - 10:40 p.m.MEX-VVI
18h 40m1 stop
Copa Airlines Logo
11:44 a.m. - 10:00 p.m.VVI-MEX
12h 16m1 stop
C$ 876Copa Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Mexico City to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Mexico City to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Mexico City to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Mexico City to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Mexico City to Santa Cruz de la Sierra is May, where tickets cost C$ 729 (return) on average. On the other hand, the most expensive months are December and January, where the average cost of round-trip tickets is C$ 918 and C$ 869 respectively.

How far in advance should I book a flight from Mexico City to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Mexico City to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Mexico City to Santa Cruz de la Sierra, you should book around 4 weeks before departure, which saves you about 25% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flightC$ 337
Best time to beat the crowds (9% less expensive on average)
Most popular time to fly (13% more expensive on average)
Flight from Mexico City to Santa Cruz de la Sierra

When to book flights from Mexico City to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Mexico City to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Mexico City to Santa Cruz de la Sierra

  • What is the cheapest flight from Mexico City to Santa Cruz de la Sierra?

    In the last 3 days, the lowest price for a flight from Mexico City to Santa Cruz de la Sierra was C$ 245 for a one-way ticket and C$ 574 for a round-trip.

  • Which airports will I be using when flying from Mexico City to Santa Cruz de la Sierra?

    Mexico City airport is called Mexico City Benito Juarez and the only airport in Santa Cruz de la Sierra is Santa Cruz de la Sierra Viru Viru Intl.

  • Which aircraft models fly most regularly from Mexico City to Santa Cruz de la Sierra?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Mexico City to Santa Cruz de la Sierra?

    Star Alliance is the only airline alliance operating flights between Mexico City and Santa Cruz de la Sierra.

  • Which is the best airline for flights from Mexico City to Santa Cruz de la Sierra, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Mexico City to Santa Cruz de la Sierra are Copa Airlines and Avianca. With an average price for the route of C$ 773 and an overall rating of 7.5, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of C$ 800 and an overall rating of 6.7.

  • How does KAYAK find such low prices on flights from Mexico City to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Mexico City to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Mexico City to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Mexico City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Mexico City to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Mexico City with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Mexico City to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Mexico City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Mexico City to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Mexico City to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Mexico City to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1500 reviews
7.4Comfort
8.1Crew
6.8Entertainment
7.8Boarding
6.8Food
Airline reviews

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

2.0 MediocreAnonymous, Jul 2025ASU - PTY
Read more Copa Airlines reviews

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Great experience with a crew always thinking in the passenger

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

I selected first class expecting excetional service. It was mediocre at best. The food service was cold, meal choices was poor and on one leg they did provide dessert. I did enjoy the lay day seat but the movies were old and nothing current. Boarding the plane is always hot. So boarding is quite warm until your in the air. I took a small personal air fan. Update the meals and movies.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

Seats not reclining, no vegetarian food option, no snacks. 7.5 hr flight should have been more comfortable. Luggage limits are unusually small. Will never fly Copa again and will tell friends and family to avoid this airline.

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

We had a five hour layover in the way home from Colombia. I read the "bout your flight" email carefully before we checked bags. We had to go through security right at the gate. Almost lost our ground coffee because that airport only allows 16 ounce of coffee and we had 18. I've been to 48 countries and never heard of a coffee restriction. I can't follow a rule I don't know about. I requested they bring our coffee to our checked luggage. Instead tey gate checked our bag for free. Back to planning transfers in Dallas I guess

It was ok. However, the food was quite poor since I don't eat pasta.

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Not what it used to be. The sale of food makes them look greedy!

Avianca is not what it used to be. So disappointing

why did we have to go through security mid flight

Seats are very tight even in Plus, no complimentary snacks or beverage

Flight to Bogotá delayed by 3 h Missed connection from Bogotá to Guayaquil. Avianca unable to bring us to Baltra on time Overall delay 36h. We missed boat departure from galagos. Overall 10 day trip needed to be cancelled. Avianca was completely un-professional.

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

Excellent flight and one of the smoothest landing I’ve ever experienced

The seats were very uncomfortable. I would have upgrade or got different flight if I knew. I usually sleep in the plane but I couldn’t sleep at all. Very uncomfortable. Also no food or drink everything was to purchase, and that’s u usual for international flight.

Boarding was somewhat confusing in that the wrong messages were being displayed at the gate. It was somewhat annoying that I got off one flight and straight onto another (from the same gate), but in between they re-checked my hand luggage and made me get rid of my water (which they charge for on the plane). I was sitting in their 'Plus' seating, but the leg room was still too small to be able to sit square. The food options on the flights are pretty cheap quality (but not price). They got me from 'A' to 'B' on-time and for a relatively good price, but the experience itself was below average.

Everything you need to know for your flight from Mexico City to Santa Cruz de la Sierra

Information on your arrival and departure airports

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