CLO - SDQ

C$ 465 Find Cheap Flights from Cali to Santo Domingo – Compare and Save

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Everything you should know

Cheapest round-trip
C$ 591
Typical prices: C$ 540-C$ 658
Copa Airlines
Sun 11/11Sun 18/11
CLO - SDQ • 1 stop
Cheapest one-way flights
C$ 465
Typical prices: C$ 337-C$ 463
Copa Airlines
Tue 13/11
CLO - SDQ • 1 stop
Direct flights
Not available
There are currently no direct flights between Cali and Santo Domingo. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
17 weeks
in advance
Our data shows that travellers who book at least 17 weeks in advance save around 17% compared to booking last minute.
Insights
Insights
When to travel
February
Cheapest • 14% price drop
December
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Medellín Jose Maria Cordova Intl (MDE)
Cheapest • Avg C$ 577 (round-trip)
Panama City Tocumen Intl (PTY)
Shortest trip • 6h 19m (one-way)
Insights
Insights
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KAYAK searches hundreds of sites at once to find you the best travel deals.
We hope you enjoy your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Cali to Santo Domingo (CLO-SDQ)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Cali to Santo Domingo

Wed, 11 Nov - Wed, 18 Nov
Copa Airlines Logo
3:01 p.m. - 2:08 a.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
10h 07m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:06 p.m. - 5:04 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
22h 58m1 stop Panama City Tocumen Intl
C$ 591Copa Airlines
20 hours ago
Fri, 20 Nov - Wed, 25 Nov
Copa Airlines Logo
6:14 p.m. - 11:45 a.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
16h 31m1 stop Panama City Tocumen Intl
Copa Airlines Logo
8:55 a.m. - 5:04 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
9h 09m1 stop Panama City Tocumen Intl
C$ 592Copa Airlines
17 hours ago
Sun, 15 Nov - Wed, 18 Nov
Copa Airlines Logo
3:01 p.m. - 10:58 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
6h 57m1 stop Panama City Tocumen Intl
Copa Airlines Logo
2:20 p.m. - 10:57 a.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
21h 37m1 stop Panama City Tocumen Intl
C$ 607Copa Airlines
2 days ago
Mon, 22 Feb - Mon, 1 Mar
Copa Airlines Logo
11:58 a.m. - 11:02 a.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
22h 04m1 stop Panama City Tocumen Intl
Copa Airlines Logo
2:20 p.m. - 11:00 a.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
21h 40m1 stop Panama City Tocumen Intl
C$ 649Copa Airlines
1 day ago
Sun, 15 Nov - Thu, 19 Nov
Copa Airlines Logo
8:42 a.m. - 10:58 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
13h 16m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:45 p.m. - 10:57 a.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
23h 12m1 stop Panama City Tocumen Intl
C$ 665Copa Airlines
1 day ago
Sat, 26 Dec - Thu, 7 Jan
Copa Airlines Logo
12:02 p.m. - 10:58 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
9h 56m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:06 p.m. - 5:34 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
6h 28m1 stop Panama City Tocumen Intl
C$ 680Copa Airlines
6 hours ago
Fri, 1 Jan - Mon, 11 Jan
Copa Airlines Logo
8:41 a.m. - 10:54 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
13h 13m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:05 p.m. - 11:00 a.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
16h 55m1 stop Panama City Tocumen Intl
C$ 695Copa Airlines
1 day ago
Mon, 5 Apr - Mon, 12 Apr
Copa Airlines Logo
6:29 p.m. - 3:48 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
20h 19m1 stop Panama City Tocumen Intl
Copa Airlines Logo
8:40 a.m. - 5:19 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
9h 39m1 stop Panama City Tocumen Intl
C$ 707Copa Airlines
3+ days ago
Mon, 8 Mar - Sun, 14 Mar
Copa Airlines Logo
5:09 a.m. - 3:48 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
9h 39m1 stop Panama City Tocumen Intl
Copa Airlines Logo
5:54 a.m. - 2:14 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
9h 20m1 stop Panama City Tocumen Intl
C$ 708Copa Airlines
1 day ago
Thu, 26 Nov - Mon, 30 Nov
Copa Airlines Logo
12:05 p.m. - 10:58 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
9h 53m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:45 p.m. - 11:01 a.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
23h 16m1 stop Panama City Tocumen Intl
C$ 728Copa Airlines
10 hours ago
Booking Insights

Price, demand, and travel trends for Cali to Santo Domingo flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Cali to Santo Domingo?

Round-trip flights from Cali to Santo Domingo typically range from C$ 540 to C$ 658. The lowest price found in the past 5 days was C$ 591, on Copa Airlines.

What's the cheapest day of the week to fly from Cali to Santo Domingo?

Based on deals KAYAK users found in the last 12 months, Friday is the cheapest day of the week to fly from Cali to Santo Domingo. It's 2% cheaper than the average day, while Sunday is the most expensive, with prices 15% higher.

What is the cheapest month to fly from Cali to Santo Domingo?

•February is the cheapest month to fly from Cali to Santo Domingo at C$ 492 round-trip.
•July (C$ 630) and December (C$ 610) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 28% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Cali to Santo Domingo the cheapest?

Flights from Cali to Santo Domingo are cheapest 17 weeks before departure. Booking in this window typically costs about 17% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for Cali to Santo Domingo flights

Low season

March

Cheapest flight

C$ 465
Beat the crowds with an average 30% drop in traveller numbers.
The most popular month to fly with an average 45% increase in traveller numbers.
One-way flight from Cali to Santo Domingo

When to book flights from Cali to Santo Domingo

Are your dates flexible? Find out the best times to travel from Cali to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Cali to Santo Domingo flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines, and booking tips.

  • How long does a flight from Cali to Santo Domingo take?

    A direct flight from Cali to Santo Domingo takes 00m, covering 2,910 km.

  • Do I need a passport to fly from Cali to Santo Domingo?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Cali to Santo Domingo flight?

    Round-trip flights from Cali to Santo Domingo range from C$ 540 to C$ 658, with an average of C$ 572 over the past 12 months. Anything below C$ 540 counts as a good deal.

  • How expensive are last-minute Cali to Santo Domingo flights?

    Last-minute fares on this route (booked within two weeks of departure) run 14% above the C$ 572 route average. Book 17 weeks before departure for the lowest fares.

  • Have flight prices from Cali to Santo Domingo changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about C$ 591 to C$ 1,126. That means the highest observed fare was about 90% higher than the lowest one.

  • How are flight prices from Cali to Santo Domingo looking right now?

    One-way fares from Cali to Santo Domingo are currently higher than usual. Average one-way flight prices are about C$ 972, which is 155% above the typical average for this route.

  • What car rental options are available at Santo Domingo Las Americas Airport (SDQ)?

    Santo Domingo Las Americas Airport (SDQ) hosts 5 major car rental companies, with daily rates averaging C$ 43 for economy cars. Top options include:

    • Zezgo
    • America Car Rental
    • JUMBO CAR
    • Infinity Car Rental
    • Final Rentals

  • Which airports can I use when flying from Cali to Santo Domingo?

    Flights from Cali to Santo Domingo usually depart from Cali Alfonso B. Aragon Intl (CLO) and arrive at Santo Domingo Las Americas (SDQ).

  • Which airports do connecting flights from Cali to Santo Domingo pass through?

    One-stop flights from Cali to Santo Domingo most commonly connect through:

    • Panama City Tocumen Intl (PTY) – 62% of one-stop connections
    • Bogotá El Dorado (BOG) – 35% of one-stop connections
    • Medellín Jose Maria Cordova Intl (MDE) – 3% of one-stop connections

  • Can I save money by using flexible dates for flights from Cali to Santo Domingo?

    Yes. Flexible dates can save you up to 15% on flights from Cali to Santo Domingo. Friday is the cheapest departure day at C$ 560 round-trip on average, while Sunday is the most expensive at C$ 658, a difference of C$ 98.

    KAYAK's flexible dates feature shows options up to three days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport when travelling from Cali to Santo Domingo?

    Flying via Panama City Tocumen Intl (PTY) gives the shortest average 1-stop total travel time at 6h 19m, compared with 6h 21m via Bogotá El Dorado (BOG) and 9h 23m via Medellín Jose Maria Cordova Intl (MDE).

  • What is the time difference between Cali and Santo Domingo?

    Santo Domingo is 1 hour ahead of Cali (Atlantic Time vs Colombia Time). Plan for the time shift when scheduling connections or first-day activities.

  • Which popular places can I visit in Santo Domingo?

    Centro Olimpico Juan Pablo Duarte is one of the most viewed places in Santo Domingo on KAYAK.

Your guide to booking Cali to Santo Domingo flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Friday departure and avoid flying on Sunday. On this route, Friday flights average C$ 560, about C$ 98 less than Sunday fares (15% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 17 weeks before you fly. On this route, that window historically saves about 17% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Cali to Santo Domingo trip for February. Fares historically average C$ 492 round-trip in that month – typically C$ 138 less than the most expensive month, which is July (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santo Domingo Las Americas Airport.

    • Hampton by Hilton Santo Domingo Airport

More options for your flight from Cali to Santo Domingo

Complete your trip to Santo Domingo with a hotel stay or car rental

Car rentals in Santo Domingo
Hotels in Santo Domingo
Vacations in Santo Domingo