CLO - SDQ

C$ 458 Find Cheap Flights from Cali to Santo Domingo – Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
C$ 583
Typical prices: C$ 518-C$ 635
Copa Airlines
Mon 24/9Wed 24/10
CLO - SDQ • 1 stop
Cheapest one-way flights
C$ 458
Typical prices: C$ 321-C$ 466
Copa Airlines
Wed 3/10
CLO - SDQ • 1 stop
Direct flights
Not available
There are currently no direct flights between Cali and Santo Domingo. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
24 weeks
in advance
Our data shows that travellers who book at least 24 weeks in advance save around 15% compared to booking last minute.
Insights
Insights
When to travel
February
Cheapest • 12% price drop
December
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Medellín Jose Maria Cordova Intl (MDE)
Cheapest • Avg C$ 552 (round-trip)
Bogotá El Dorado (BOG)
Shortest trip • 6h 16m (one-way)
Insights
Insights
Start a new search
KAYAK searches hundreds of sites at once to find you the best travel deals.
We hope you enjoy your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Cali to Santo Domingo (CLO-SDQ)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Cali to Santo Domingo

Thu, 24 Sep - Wed, 30 Sep
Copa Airlines Logo
12:08 p.m. - 10:56 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
9h 48m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:41 p.m. - 5:21 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
23h 40m1 stop Panama City Tocumen Intl
C$ 583Copa Airlines
Thu, 29 Oct - Thu, 29 Oct
Copa Airlines Logo
4:40 a.m. - 1:12 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
7h 32m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:07 p.m. - 11:02 a.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
16h 55m1 stop Panama City Tocumen Intl
C$ 598Copa Airlines
Wed, 27 Jan - Sat, 6 Feb
Multiple Airlines Logo
4:03 p.m. - 11:57 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
6h 54m1 stop Medellín Jose Maria Cordova Intl
Multiple Airlines Logo
7:35 a.m. - 2:30 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
7h 55m2 stops Bogotá El Dorado Medellín Jose Maria Cordova Intl
C$ 626Multiple Airlines
Sun, 20 Sep - Thu, 1 Oct
Copa Airlines Logo
12:08 p.m. - 10:55 a.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
21h 47m1 stop Panama City Tocumen Intl
Copa Airlines Logo
8:47 a.m. - 11:37 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
15h 50m1 stop Panama City Tocumen Intl
C$ 633Copa Airlines
Sun, 7 Feb - Tue, 23 Feb
Copa Airlines Logo
4:36 a.m. - 4:08 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
10h 32m1 stop Panama City Tocumen Intl
Copa Airlines Logo
5:53 a.m. - 5:33 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
12h 40m1 stop Panama City Tocumen Intl
C$ 652Copa Airlines
Mon, 5 Oct - Sun, 11 Oct
Copa Airlines Logo
6:36 p.m. - 11:41 a.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
16h 05m1 stop Panama City Tocumen Intl
Copa Airlines Logo
8:47 a.m. - 2:10 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
6h 23m1 stop Panama City Tocumen Intl
C$ 676Copa Airlines
Mon, 5 Oct - Mon, 12 Oct
Copa Airlines Logo
3:10 p.m. - 1:12 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
21h 02m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:41 p.m. - 2:10 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
20h 29m1 stop Panama City Tocumen Intl
C$ 767Copa Airlines
Tue, 6 Oct - Mon, 12 Oct
Copa Airlines Logo
8:46 a.m. - 4:14 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
6h 28m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:41 p.m. - 2:10 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
20h 29m1 stop Panama City Tocumen Intl
C$ 768Copa Airlines
Wed, 27 Jan - Sat, 6 Feb
Multiple Airlines Logo
12:50 p.m. - 11:57 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
10h 07m2 stops Bogotá El Dorado Medellín Jose Maria Cordova Intl
Multiple Airlines Logo
7:35 a.m. - 7:05 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
12h 30m2 stops Bogotá El Dorado Medellín Jose Maria Cordova Intl
C$ 798Multiple Airlines
Sun, 3 Jan - Tue, 19 Jan
United Airlines Logo
4:38 a.m. - 11:46 p.m.CLO  Cali Alfonso B. Aragon Intl-SDQ Santo Domingo Las Americas
18h 08m2 stops Panama City Tocumen Intl Newark
United Airlines Logo
2:53 p.m. - 5:34 p.m.SDQ  Santo Domingo Las Americas-CLO Cali Alfonso B. Aragon Intl
27h 41m3 stops Newark Houston George Bush Intcntl Panama City Tocumen Intl
C$ 8,837United Airlines
Booking Insights

Price, demand, and travel trends for Cali to Santo Domingo flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights from Cali to Santo Domingo with more confidence.

How much is a round-trip flight from Cali to Santo Domingo?

Round-trip flights from Cali to Santo Domingo start at C$ 583. Prices are typical for this route right now, with typical round-trip fares ranging from C$ 518 to C$ 635. The lowest price found in the past 5 days was C$ 583 on Copa Airlines.

What's the cheapest day of the week to fly from Cali to Santo Domingo?

Thursday is the cheapest day of the week to fly from Cali to Santo Domingo and is 3% cheaper than the average day. Sunday is the most expensive day with flight prices 13% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Cali to Santo Domingo?

  • February is the cheapest month to fly from Cali to Santo Domingo at C$ 485 round-trip.
  • July (C$ 622) and April (C$ 593) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 28% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Cali to Santo Domingo the cheapest?

Flights from Cali to Santo Domingo are cheapest 24 weeks before departure. Booking in this window typically costs about 15% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for Cali to Santo Domingo flights

Low season

March

Cheapest flight

C$ 458
Best time to beat the crowds (2% less expensive on average)
Most popular time to fly (7% more expensive on average)
Flights from Cali to Santo Domingo

When to book flights from Cali to Santo Domingo

Are your dates flexible? Find out the best times to travel from Cali to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Cali to Santo Domingo flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines, and booking questions.

  • Which airports can I use when flying from Cali to Santo Domingo?

    Flights from Cali to Santo Domingo usually depart from Cali Alfonso B. Aragon Intl (CLO) and arrive at Santo Domingo Las Americas (SDQ).

  • Which airports do connecting flights from Cali to Santo Domingo pass through?

    One-stop flights from Cali to Santo Domingo most commonly connect through:

    • Panama City Tocumen Intl (PTY) – 59% of one-stop connections
    • Bogotá El Dorado (BOG) – 39% of one-stop connections
    • Medellín Jose Maria Cordova Intl (MDE) – 2% of one-stop connections

    Panama City Tocumen Intl (PTY) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Cali to Santo Domingo?

    Yes. Being flexible with your travel dates can save you up to 14% on the Cali to Santo Domingo route. Thursday is the cheapest departure day at C$ 538 round-trip on average, while Sunday is the most expensive at C$ 623, a difference of C$ 85. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • Which popular places can I visit in Santo Domingo?

    Some of the most popular sights in Santo Domingo are Embassy of the United States Dominican Republic and Centro Olimpico Juan Pablo Duarte. These are among the most viewed places in Santo Domingo on KAYAK.

  • How expensive are last-minute Cali to Santo Domingo flights?

    Last-minute fares on this route – booked within 2 weeks of departure – run 13% above the route average of C$ 550. Book 24 weeks before departure for the lowest fares.

  • How long does a flight from Cali to Santo Domingo take?

    A direct flight from Cali to Santo Domingo takes 0h 00m, covering 2,910 km.

  • Do I need a passport to fly from Cali to Santo Domingo?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How are flight prices from Cali to Santo Domingo looking right now?

    One-way fares from Cali to Santo Domingo are currently higher than usual. Average one-way flight prices are about C$ 458, which is 22% above the typical average for this route.

  • How much time can I save by choosing a different layover airport when travelling from Cali to Santo Domingo?

    Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 6h 16m, compared with 6h 18m via Panama City Tocumen Intl (PTY) and 10h 12m via Medellín Jose Maria Cordova Intl (MDE).

  • What is the time difference between Cali and Santo Domingo?

    Santo Domingo is 1 hour ahead of Cali (Atlantic Time vs Colombia Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Santo Domingo Las Americas Airport (SDQ)?

    Santo Domingo Las Americas Airport (SDQ) hosts 5 major car rental companies, with daily rates starting from around C$ 10 for economy cars. Top options include:
    · Zezgo
    · America Car Rental
    · JUMBO CAR
    · Infinity Car Rental
    · Final Rentals

  • How much should I expect to pay for a Cali to Santo Domingo flight?

    Round-trip flights from Cali to Santo Domingo range from C$ 518 to C$ 635, with an average of C$ 550 over the past 12 months. Anything below C$ 518 counts as a good deal.

Your guide to booking Cali to Santo Domingo flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure instead of Sunday. On this route, Thursday flights average C$ 538 – about C$ 85 less than Sunday (14% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 24 weeks before you fly. On this route, that window historically saves about 15% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Cali to Santo Domingo trip for February. Fares historically average C$ 485 round-trip in that month – typically C$ 136 less than the most expensive month, which is July (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santo Domingo Las Americas Airport.
    - Hampton by Hilton Santo Domingo Airport

More options for your flight from Cali to Santo Domingo

Complete your trip to Santo Domingo with a hotel stay or car rental

Car rentals in Santo Domingo
Hotels in Santo Domingo
Vacations in Santo Domingo