C$ 37 Find Cheap Flights from Santiago to La Serena – Compare and Save

These are the earliest and latest flight times available from Santiago to La Serena:

• Earliest: departs at 6:00 am and lands at 7:10 am
• Latest: departs at 9:26 pm and lands at 10:36 pm.

The flight takes about 1h 10m.

Only Economy Class is available on flights from Santiago to La Serena.

A direct flight from Santiago to La Serena takes 1h 10m, covering 625 km.

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Round-trip flights from Santiago to La Serena range from C$ 82 to C$ 126, with an average of C$ 99 over the past 12 months. Anything below C$ 82 counts as a good deal.

Last-minute fares on this route – booked within 2 weeks of departure – run 28% above the route average of C$ 99. Book 22 weeks before departure for the lowest fares.

Sky Airline is slightly above the route average for timely arrivals, while LATAM Airlines has a lower on-time arrival rate. On-time arrival rates on Santiago to La Serena flights are:

• Sky Airline: 92% on time
• LATAM Airlines: 92% on time
• JetSMART: 90% on time

On average, flights on this route are punctual 92% of the time.

There is no standard. Checked bag policies vary by airline on this route. Most carriers charge C$ 28–C$ 141 for the first checked bag in economy. Premium fares and elite status bookings typically include a free checked bag.

The Airbus A320-100/200 family is used most often on this route, operated mainly by LATAM Airlines and JetSMART. Other aircraft seen on the route include Airbus A321-100/200 variants.

Morning is the busiest departure period on Santiago to La Serena flights, with 38% leaving in that window. Afternoon departures account for 37%, Evening flights for 25%, and Night flights for 0%.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about C$ 72 to C$ 374. That means the highest observed fare was about 5x higher than the lowest one.

One-way fares from Santiago to La Serena are currently higher than usual. Average one-way flight prices are about C$ 66, which is 21% above the typical average for this route.

La Serena La Florida Airport (LSC) hosts 5 major car rental companies, with daily rates starting from around C$ 13 for economy cars. Top options include:
• Street Rent a Car
• Gama Rent
• Sixt
• Mitta Rent a Car
• Budget

Flights from Santiago to La Serena usually depart from Santiago Arturo Merino Benitez (SCL) and arrive at La Serena La Florida (LSC).

Morning flights have the fewest delays on this route. Delays tend to pile up throughout the day as one late flight pushes the next, so earlier departures are usually more reliable.

A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Santiago to La Serena route, 8% of flights were delayed in the past 3 months, with delays averaging 1 hour 30 minutes.

Yes. Being flexible with your travel dates can save you up to 11% on the Santiago to La Serena route. Tuesday is the cheapest departure day at C$ 93 round-trip on average, while Thursday is the most expensive at C$ 105, a difference of C$ 11. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

3 airlines operate flights between Santiago and La Serena. The airlines offering direct flights on this route include:

• LATAM Airlines
• Sky Airline
• JetSMART

Among airlines operating Santiago to La Serena flights:

• Sky Airline: offers free seat selection
• LATAM Airlines: offers extra legroom; offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Here are some options for this route, based on selected ticket types and cabin classes:

• Sky Airline: a carry-on bag and a checked bag in Economy Class
• LATAM Airlines: a carry-on bag and a checked bag in Economy Class
• JetSMART: a cabin bag in Economy Class class

Bag allowance can vary by ticket type, cabin class, route, and airline, so travellers should check the fare details before booking.