C$ 300 Find Cheap Flights from Cali to Panama City – Compare and Save

These are the earliest and latest flight times available from Cali to Panama City:

• Earliest: departs at 4:38 am and lands at 6:15 am
• Latest: departs at 6:38 pm and lands at 8:15 pm.

The flight takes about 1h 37m.

A direct flight from Cali to Panama City takes 1h 37m, covering 1,123 km.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Round-trip flights from Cali to Panama City range from C$ 388 to C$ 524, with an average of C$ 442 over the past 12 months. Anything below C$ 388 counts as a good deal.

Last-minute fares on this route – booked within 2 weeks of departure – run 7% above the route average of C$ 442. Book 6 weeks before departure for the lowest fares.

On this route, direct and layover fares are close on average, with direct at C$ 442 round-trip and layover options via Bogotá El Dorado (BOG) at C$ 447.

Copa Airlines is the only airline operating Cali to Panama City flights. 97% of its flights are on time.

There is no standard. Checked bag policies vary by airline on this route. Most carriers charge C$ 98–C$ 141 for the first checked bag in economy. Premium fares and elite status bookings typically include a free checked bag.

The Boeing 737-800 family is used most often on this route, operated mainly by Copa Airlines and Wingo. Other aircraft seen on the route include Airbus A320-100/200 variants.

Afternoon is the busiest departure period on Cali to Panama City flights, with 40% leaving in that window. Morning departures account for 20%, Evening flights for 20%, and Night flights for 20%.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about C$ 511 to C$ 1,166. That means the highest observed fare was about 2x higher than the lowest one.

One-way fares from Cali to Panama City are currently higher than usual. Average one-way flight prices are about C$ 301, which is 10% above the typical average for this route.

Panama City Tocumen Intl Airport (PTY) hosts 5 major car rental companies, with daily rates starting from around C$ 2 for economy cars. Top options include:
• Avis
• Europcar
• Ace
• Budget
• Hertz

Flights from Cali to Panama City usually depart from Cali Alfonso B. Aragon Intl (CLO) and arrive at Panama City Tocumen Intl (PTY).

Morning flights have the fewest delays on this route. Delays tend to pile up throughout the day as one late flight pushes the next, so earlier departures are usually more reliable.

A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Cali to Panama City route, 3% of flights were delayed in the past 3 months, with delays averaging 1 hour 39 minutes.

One-stop flights from Cali to Panama City most commonly connect through:

• Bogotá El Dorado (BOG) – 99% of one-stop connections
• Medellín Jose Maria Cordova Intl (MDE) – 0% of one-stop connections
• Mexico City Benito Juarez (MEX) – 0% of one-stop connections

Bogotá El Dorado (BOG) handles the largest share of one-stop connections on this route.

Yes. Being flexible with your travel dates can save you up to 6% on the Cali to Panama City route. Tuesday is the cheapest departure day at C$ 434 round-trip on average, while Sunday is the most expensive at C$ 459, a difference of C$ 25. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Only Copa Airlines operates flights between Cali and Panama City.

Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 4h 34m, compared with 12h 43m via Medellín Jose Maria Cordova Intl (MDE) and 28h 42m via Mexico City Benito Juarez (MEX).

Among airlines operating Cali to Panama City flights:

• Copa Airlines: offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Here are some options for this route, based on selected ticket types and cabin classes:

• Copa Airlines: a carry-on bag and a checked bag in Economy Class

Bag allowance can vary by ticket type, cabin class, route, and airline, so travellers should check the fare details before booking.