C$ 327 Find Cheap Flights from Cartagena to Panama City – Compare and Save

Among airlines operating Cartagena to Panama City flights:

• Copa Airlines: offers extra legroom; offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Only Copa Airlines operates flights between Cartagena and Panama City.

Flights from Cartagena to Panama City usually depart from Cartagena Rafael Nunez (CTG) and arrive at Panama City Tocumen Intl (PTY).

Here are some options for this route, based on selected ticket types and cabin classes:

• Copa Airlines: a carry-on bag and a checked bag in Economy Class

Bag allowance can vary by ticket type, cabin class, route, and airline, so travellers should check the fare details before booking.

On this route, layover flights are cheaper than direct options on average. Layover fares average C$ 402 round-trip via Medellín Jose Maria Cordova Intl (MDE), compared to C$ 452 for direct.

There is no standard. Checked bag policies vary by airline on this route. Most carriers charge C$ 128–C$ 140 for the first checked bag in economy. Premium fares and elite status bookings typically include a free checked bag.

The Boeing 737-800 family is used most often on this route, operated mainly by Copa Airlines and Wingo. Other aircraft seen on the route include Boeing 737 MAX 9 variants.

Connecting flights from Cartagena to Panama City most commonly pass through:

• Bogotá El Dorado (BOG) – 98% of one-stop connections
• Medellín Jose Maria Cordova Intl (MDE) – 2% of one-stop connections
Together, these airports account for 100% of one-stop bookings on this route.

On the Cartagena to Panama City route, being flexible with your departure day can save you up to 14%. Saturday is the cheapest day at C$ 427 round-trip on average, while Sunday is the most expensive at C$ 492 – a C$ 66 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Cartagena to Panama City route, 2% of flights were delayed in the past 3 months, with delays averaging 1 hour 34 minutes.

Morning is the busiest departure period on Cartagena to Panama City flights, with 50% leaving in that window. Afternoon departures account for 50%, Evening flights for 0%, and Night flights for 0%.

These are the earliest and latest flight times available from Cartagena to Panama City:

• Earliest: departs at 6:20 am and lands at 7:40 am
• Latest: departs at 7:05 pm and lands at 8:25 pm.

The flight takes about 1h 20m.

Last-minute fares on this route – booked within 2 weeks of departure – run 9% above the route average of C$ 454. Book 18 weeks before departure for the lowest fares.

A direct flight from Cartagena to Panama City takes 1h 20m, covering 725 km.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about C$ 560 to C$ 1,403. That means the highest observed fare was about 3x higher than the lowest one.

One-way fares from Cartagena to Panama City are currently higher than usual. Average one-way flight prices are about C$ 345, which is 23% above the typical average for this route.

Copa Airlines is the only airline operating Cartagena to Panama City flights. 98% of its flights are on time.

Night flights have the fewest delays on this route. Delays tend to pile up throughout the day as one late flight pushes the next, so earlier departures are usually more reliable.

Flying via Medellín Jose Maria Cordova Intl (MDE) gives the shortest average 1-stop total travel time at 4h 05m, compared with 5h 01m via Bogotá El Dorado (BOG).

Panama City Tocumen Intl Airport (PTY) hosts 5 major car rental companies, with daily rates starting from around C$ 2 for economy cars. Top options include:
• Avis
• Europcar
• Ace
• Budget
• Hertz

Round-trip flights from Cartagena to Panama City range from C$ 417 to C$ 556, with an average of C$ 454 over the past 12 months. Anything below C$ 417 counts as a good deal.