C$ 527 Find Cheap Flights from Mexico City to Santiago – Compare and Save

These are the earliest and latest flight times available from Mexico City to Santiago:

• Earliest: departs at 9:55 am and lands at 6:17 pm
• Latest: departs at 8:05 pm and lands at 4:27 am.

The flight takes about 8h 22m.

Only Economy Class is available on flights from Mexico City to Santiago.

A direct flight from Mexico City to Santiago takes 8h 22m, covering 10,609 km.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Round-trip flights from Mexico City to Santiago range from C$ 842 to C$ 1,176, with an average of C$ 1,005 over the past 12 months. Anything below C$ 842 counts as a good deal.

Last-minute fares on this route – booked within 2 weeks of departure – run 9% above the route average of C$ 1,005. Book 9 weeks before departure for the lowest fares.

On this route, layover flights are cheaper than direct options on average. Layover fares average C$ 923 round-trip via Lima J Chavez Intl (LIM), compared to C$ 1,042 for direct.

Aeromexico is the only airline operating Mexico City to Santiago flights. 92% of its flights are on time.

There is no standard. Checked bag policies vary by airline on this route. Most carriers charge C$ 83–C$ 142 for the first checked bag in economy. Premium fares and elite status bookings typically include a free checked bag.

The Airbus A330 family is used most often on this route, operated mainly by LATAM Airlines and Aerolineas Argentinas. Other aircraft seen on the route include Boeing 787-9 Dreamliner variants.

Morning is the busiest departure period on Mexico City to Santiago flights, with 50% leaving in that window. Evening departures account for 50%, Afternoon flights for 0%, and Night flights for 0%.

One-way fares from Mexico City to Santiago are currently higher than usual. Average one-way flight prices are about C$ 966, which is 81% above the typical average for this route.

Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car rental companies, with daily rates starting from around C$ 8 for economy cars. Top options include:
• Lucano
• United Rent-A-Car
• Rosselot
• FlexWays
• Alamo

Flights from Mexico City to Santiago usually depart from Mexico City Benito Juarez (MEX) and arrive at Santiago Arturo Merino Benitez (SCL).

Morning flights have the fewest delays on this route. Delays tend to pile up throughout the day as one late flight pushes the next, so earlier departures are usually more reliable.

A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Mexico City to Santiago route, 8% of flights were delayed in the past 3 months, with delays averaging 3 hours 1 minute.

One-stop flights from Mexico City to Santiago most commonly connect through:

• Bogotá El Dorado (BOG) – 64% of one-stop connections
• Panama City Tocumen Intl (PTY) – 29% of one-stop connections
• Lima J Chavez Intl (LIM) – 7% of one-stop connections

Bogotá El Dorado (BOG) handles the largest share of one-stop connections on this route.

Yes. Being flexible with your travel dates can save you up to 9% on the Mexico City to Santiago route. Monday is the cheapest departure day at C$ 976 round-trip on average, while Saturday is the most expensive at C$ 1,068, a difference of C$ 92. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

2 airlines operate flights between Mexico City and Santiago. The airlines offering direct flights on this route include:

• LATAM Airlines
• Aeromexico

Flying via Panama City Tocumen Intl (PTY) gives the shortest average 1-stop total travel time at 13h 24m, compared with 13h 31m via Bogotá El Dorado (BOG) and 17h 35m via Lima J Chavez Intl (LIM).

Santiago is 3 hours ahead of Mexico City (Chile Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

Costanera Center is one of the most viewed places in Santiago on KAYAK.

Among airlines operating Mexico City to Santiago flights:

• LATAM Airlines: offers extra legroom; offers free seat selection
• Aeromexico: offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Here are some options for this route, based on selected ticket types and cabin classes:

• LATAM Airlines: a carry-on bag and a checked bag in Economy Class
• Aeromexico: a carry-on bag and a checked bag in Economy Class
• AeroMexico Connect: a cabin bag in Economy Class class

Bag allowance can vary by ticket type, cabin class, route, and airline, so travellers should check the fare details before booking.