C$ 389 Find Cheap Flights from Panama City to Santo Domingo – Compare and Save

Among airlines operating Panama City to Santo Domingo flights:

• Copa Airlines: offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Only Copa Airlines operates flights between Panama City and Santo Domingo.

Flights from Panama City to Santo Domingo usually depart from Panama City Tocumen Intl (PTY) and arrive at Santo Domingo Las Americas (SDQ).

Here are some options for this route, based on selected ticket types and cabin classes:

• Copa Airlines: a carry-on bag and a checked bag in Economy Class

Bag allowance can vary by ticket type, cabin class, route, and airline, so travellers should check the fare details before booking.

Only Economy Class is available on flights from Panama City to Santo Domingo.

On this route, direct and layover fares are close on average, with direct at C$ 671 round-trip and layover options via Bogotá El Dorado (BOG) at C$ 649.

There is no standard. Checked bag policies vary by airline on this route. Most carriers charge C$ 138–C$ 138 for the first checked bag in economy. Premium fares and elite status bookings typically include a free checked bag.

The Boeing 737-800 family is used most often on this route, operated mainly by Copa Airlines. Other aircraft seen on the route include Boeing 737 MAX 8 variants.

Connecting flights from Panama City to Santo Domingo most commonly pass through:

• Bogotá El Dorado (BOG) – 98% of one-stop connections
• Mexico City Benito Juarez (MEX) – 2% of one-stop connections
Together, these airports account for 100% of one-stop bookings on this route.

Yes. Being flexible with your travel dates can save you up to 13% on the Panama City to Santo Domingo route. Thursday is the cheapest departure day at C$ 642 round-trip on average, while Sunday is the most expensive at C$ 732, a difference of C$ 90. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Panama City to Santo Domingo route, 5% of flights were delayed in the past 3 months, with delays averaging 1 hour 52 minutes.

Morning is the busiest departure period on Panama City to Santo Domingo flights, with 60% leaving in that window. Afternoon departures account for 20%, Evening flights for 20%, and Night flights for 0%.

Some of the most popular sights in Santo Domingo are Embassy of the United States Dominican Republic and Centro Olimpico Juan Pablo Duarte. These are among the most viewed places in Santo Domingo on KAYAK.

These are the earliest and latest flight times available from Panama City to Santo Domingo:

• Earliest: departs at 7:24 am and lands at 9:54 am
• Latest: departs at 10:55 pm and lands at 1:25 am.

The flight takes about 2h 30m.

Last-minute fares on this route – booked within 2 weeks of departure – run 33% above the route average of C$ 662. Book 9 weeks before departure for the lowest fares.

A direct flight from Panama City to Santo Domingo takes 2h 30m, covering 2,375 km.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about C$ 678 to C$ 3,180. That means the highest observed fare was about 5x higher than the lowest one.

One-way fares from Panama City to Santo Domingo are currently higher than usual. Average one-way flight prices are about C$ 588, which is 14% above the typical average for this route.

Copa Airlines is the only airline operating Panama City to Santo Domingo flights. 95% of its flights are on time.

Night flights have the fewest delays on this route. Delays tend to pile up throughout the day as one late flight pushes the next, so earlier departures are usually more reliable.

Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 7h 18m, compared with 21h 21m via Mexico City Benito Juarez (MEX).

Santo Domingo is 1 hour ahead of Panama City (Atlantic Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

Santo Domingo Las Americas Airport (SDQ) hosts 5 major car rental companies, with daily rates starting from around C$ 10 for economy cars. Top options include:
· Zezgo
· America Car Rental
· JUMBO CAR
· Infinity Car Rental
· Final Rentals

Round-trip flights from Panama City to Santo Domingo range from C$ 623 to C$ 759, with an average of C$ 662 over the past 12 months. Anything below C$ 623 counts as a good deal.