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UIO - SCL

C$ 275 Find Cheap Flights from Quito to Santiago – Compare and Save

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Everything you should know

Cheapest round-trip
C$ 487
Typical prices: C$ 609-C$ 833
JetSMART
Tue 6/11Tue 13/11
UIO - SCL • 1 stop
Cheapest one-way flights
C$ 275
Typical prices: C$ 358-C$ 534
JetSMART
Tue 27/11
UIO - SCL • 1 stop
Direct flights
Not available
There are currently no direct flights between Quito and Santiago. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
7 weeks
in advance
Our data shows that travellers who book at least 7 weeks in advance save around 28% compared to booking last minute.
Insights
Insights
When to travel
November
Cheapest • 9% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Lima J Chavez Intl (LIM)
Cheapest • Avg C$ 678 (round-trip)
Guayaquil Jose Joaquin de Olmedo (GYE)
Shortest trip • 8h 27m (one-way)
Insights
Insights
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We hope you enjoy your trip to Santiago!
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Booking Insights
Flight Deals

Cheap Flights from Quito to Santiago (UIO-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Quito to Santiago

Fri, 6 Nov - Fri, 13 Nov
JetSMART Logo
4:50 p.m. - 5:05 a.m.UIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
10h 15m1 stop Lima J Chavez Intl
JetSMART Logo
6:07 a.m. - 4:05 p.m.SCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
11h 58m1 stop Lima J Chavez Intl
C$ 487JetSMART
Fri, 27 Nov - Tue, 1 Dec
JetSMART Logo
4:50 p.m. - 5:05 a.m.UIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
10h 15m1 stop Lima J Chavez Intl
JetSMART Logo
12:32 p.m. - 4:05 p.m.SCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
29h 33m1 stop Lima J Chavez Intl
C$ 521JetSMART
Sun, 22 Nov - Fri, 27 Nov
JetSMART Logo
4:50 p.m. - 5:05 a.m.UIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
10h 15m1 stop Lima J Chavez Intl
JetSMART Logo
6:07 a.m. - 4:05 p.m.SCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
11h 58m1 stop Lima J Chavez Intl
C$ 560JetSMART
Mon, 15 Feb - Mon, 22 Feb
JetSMART Logo
4:50 p.m. - 10:53 a.m.UIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
16h 03m1 stop Lima J Chavez Intl
JetSMART Logo
6:07 a.m. - 4:04 p.m.SCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
11h 57m1 stop Lima J Chavez Intl
C$ 568JetSMART
Wed, 13 Jan - Mon, 25 Jan
JetSMART Logo
4:50 p.m. - 10:53 a.m.UIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
16h 03m1 stop Lima J Chavez Intl
JetSMART Logo
6:07 a.m. - 4:04 p.m.SCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
11h 57m1 stop Lima J Chavez Intl
C$ 585JetSMART
Fri, 20 Nov - Fri, 27 Nov
Avianca Logo
1:40 p.m. - 5:45 a.m.UIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
14h 05m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado
Avianca Logo
4:15 p.m. - 11:55 p.m.SCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
9h 40m1 stop Bogotá El Dorado
C$ 605Avianca
Wed, 23 Dec - Mon, 18 Jan
JetSMART Logo
4:50 p.m. - 5:05 a.m.UIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
10h 15m1 stop Lima J Chavez Intl
JetSMART Logo
6:07 a.m. - 4:04 p.m.SCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
11h 57m1 stop Lima J Chavez Intl
C$ 614JetSMART
Wed, 3 Mar - Mon, 8 Mar
JetSMART Logo
4:50 p.m. - 8:58 p.m.UIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
26h 08m1 stop Lima J Chavez Intl
JetSMART Logo
6:07 a.m. - 4:04 p.m.SCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
11h 57m1 stop Lima J Chavez Intl
C$ 629JetSMART
Fri, 19 Mar - Mon, 22 Mar
JetSMART Logo
4:51 p.m. - 10:53 a.m.UIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
16h 02m1 stop Lima J Chavez Intl
JetSMART Logo
6:07 a.m. - 4:04 p.m.SCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
11h 57m1 stop Lima J Chavez Intl
C$ 634JetSMART
Mon, 18 Jan - Wed, 27 Jan
JetSMART Logo
4:50 p.m. - 8:58 p.m.UIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
26h 08m1 stop Lima J Chavez Intl
JetSMART Logo
6:07 a.m. - 4:04 p.m.SCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
11h 57m1 stop Lima J Chavez Intl
C$ 636JetSMART
Booking Insights

Price, demand, and travel trends for Quito to Santiago flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Quito to Santiago?

Round-trip flights from Quito to Santiago typically range from C$ 609 to C$ 833. The lowest price found in the past 5 days was C$ 487, on JetSMART.

What's the cheapest day of the week to fly from Quito to Santiago?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Quito to Santiago. It’s 9% cheaper than the average day, while Saturday is the most expensive, with prices 10% higher.

What is the cheapest month to fly from Quito to Santiago?

•November is the cheapest month to fly from Quito to Santiago at C$ 659 round-trip.
•February (C$ 833) and December (C$ 777) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 26% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Quito to Santiago the cheapest?

Flights from Quito to Santiago are cheapest 7 weeks before departure. Booking in this window typically costs about 28% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for Quito to Santiago flights

Low season

June

Cheapest flight

C$ 275
Beat the crowds with an average 36% drop in traveller numbers.
The most popular month to fly with an average 8% increase in traveller numbers.
One-way flight from Quito to Santiago

When to book flights from Quito to Santiago

Are your dates flexible? Find out the best times to travel from Quito to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Quito to Santiago flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines, and booking tips.

  • What are the earliest and latest flights from Quito to Santiago?

    These are the earliest and latest flight times available from Quito to Santiago:

    • Earliest: departs at 11:00 pm and lands at 4:00 am
    • Latest: departs at 11:00 pm and lands at 4:00 am.

    The flight takes about 5h.

  • How long does a flight from Quito to Santiago take?

    A direct flight from Quito to Santiago takes 5h, covering 6,085 km.

  • Do I need a passport to fly from Quito to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Quito to Santiago flight?

    Round-trip flights from Quito to Santiago range from C$ 609 to C$ 833, with an average of C$ 728 over the past 12 months. Anything below C$ 609 counts as a good deal.

  • How expensive are last-minute Quito to Santiago flights?

    Last-minute fares on this route (booked within two weeks of departure) run 16% above the C$ 728 route average. Book 7 weeks before departure for the lowest fares.

  • How much can I save by taking a layover when flying from Quito to Santiago?

    On this route, layover flights are cheaper than direct options on average. Layover fares average C$ 678 round-trip via Lima J Chavez Intl (LIM), compared to C$ 904 for direct.

  • What is the standard checked bag allowance on flights from Quito to Santiago?

    There is no standard. Checked bag policies vary by airline on this route. Most carriers charge C$ 85–C$ 142 for the first checked bag in economy. Premium fares and elite status bookings typically include a free checked bag.

  • How are flight prices from Quito to Santiago looking right now?

    One-way fares from Quito to Santiago are currently lower than usual. Average one-way flight prices are about C$ 369, which is 16% below the typical average for this route.

  • What car rental options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car rental companies, with daily rates starting from around C$ 9 for economy cars. Top options include:

    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • Which airports can I use when flying from Quito to Santiago?

    Flights from Quito to Santiago usually depart from Quito Mariscal Sucr (UIO) and arrive at Santiago Arturo Merino Benitez (SCL).

  • Which airports do connecting flights from Quito to Santiago pass through?

    One-stop flights from Quito to Santiago most commonly connect through:

    • Lima J Chavez Intl (LIM) – 73% of one-stop connections
    • Bogotá El Dorado (BOG) – 19% of one-stop connections
    • Panama City Tocumen Intl (PTY) – 7% of one-stop connections
    • Guayaquil Jose Joaquin de Olmedo (GYE) – 2% of one-stop connections

  • Can I save money by using flexible dates for flights from Quito to Santiago?

    Yes. Flexible dates can save you up to 18% on flights from Quito to Santiago. Wednesday is the cheapest departure day at C$ 666 round-trip on average, while Saturday is the most expensive at C$ 807, a difference of C$ 141.

    KAYAK's flexible dates feature shows options up to three days before and after your selected dates, making it easier to compare nearby fares.

  • Which airlines fly from Quito to Santiago?

    Only LATAM Airlines operates flights between Quito and Santiago.

  • How much time can I save by choosing a different layover airport when travelling from Quito to Santiago?

    Flying via Guayaquil Jose Joaquin de Olmedo (GYE) gives the shortest average 1-stop total travel time at 8h 27m, compared with 10h 05m via Bogotá El Dorado (BOG) and 10h 21m via Panama City Tocumen Intl (PTY).

  • What is the time difference between Quito and Santiago?

    Santiago is 2 hours ahead of Quito (Chile Time vs Ecuador Time). Plan for the time shift when scheduling connections or first-day activities.

  • Which popular places can I visit in Santiago?

    Costanera Center is one of the most viewed places in Santiago on KAYAK.

  • Which airlines offer extra legroom and free seat selection on Quito to Santiago flights?

    Among airlines operating Quito to Santiago flights:

    • LATAM Airlines: offers free seat selection

    Extra legroom and free seat selection availability depends on fare class and route.

  • Which airlines include bags at no extra cost on Quito to Santiago flights?

    Here are some options for this route, based on selected ticket types and cabin classes:

    • LATAM Airlines: a carry-on bag and a checked bag in Economy Class

    Baggage allowance can vary by ticket type, cabin class, route, and airline, so always check the fare details before booking.

Your guide to booking Quito to Santiago flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Saturday. On this route, Wednesday flights average C$ 666, about C$ 141 less than Saturday fares (17% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 7 weeks before you fly. On this route, that window historically saves about 28% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Quito to Santiago trip for November. Fares historically average C$ 659 round-trip in that month – typically C$ 174 less than the most expensive month, which is February (based on the last 12 months).
  • If you have the time, taking a 1-stop flight through Lima J Chavez Intl Airport (LIM) can be cheaper than flying direct. The cheapest layover option averages C$ 678 round-trip on this route – about C$ 225 less than direct flights (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.

    • Holiday Inn Santiago - Airport Terminal By IHG

Prefer to fly direct from Quito to Santiago?

 
Find which airlines fly direct from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Quito Mariscal Sucr to Santiago Arturo Merino Benitez

Tuesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more nonstop flights

Direct returns

Santiago Arturo Merino Benitez to Quito Mariscal Sucr

Tuesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more nonstop flights

More options for your flight from Quito to Santiago

Complete your trip to Santiago with a hotel stay or car rental

Car rentals in Santiago
Hotels in Santiago
Vacations in Santiago