PTY - MEX

C$ 282 Find Cheap Flights from Panama City to Mexico City – Compare and Save

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Everything you should know

Cheapest round-trip
C$ 509
Typical prices: C$ 486-C$ 708
Avianca
Wed 17/1Wed 24/1
PTY - MEX • 1 stop
Cheapest direct flights
C$ 523
Typical prices: C$ 490-C$ 722
Copa Airlines
Mon 24/12Sun 30/12
PTY - MEX • Direct
Direct flights
You can fly direct with Copa Airlines and Aeromexico. Average duration is 3h 50m
Direct flights
+1
Direct flights
+1
Avoid delays
Most punctual • 97% on-time
Best time • Fewest delays
Insights
Insights
When to book
in advance
Our data shows that travellers who book at least 12 weeks in advance save around 19% compared to booking last minute.
Insights
Insights
When to travel
Cheapest • 11% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg C$ 549 (round-trip)
Shortest trip • 7h 21m (one-way)
Insights
Insights
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We hope you enjoy your trip to Mexico City!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Panama City to Mexico City (PTY-MEX)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Mexico City

Sun, 17 Jan - Sun, 24 Jan
Avianca Logo
6:10 p.m. - 5:15 a.m.PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
12h 05m1 stop Bogotá El Dorado
Avianca Logo
8:20 a.m. - 5:15 p.m.MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
7h 55m1 stop Bogotá El Dorado
C$ 509Avianca
Sat, 10 Oct - Sat, 17 Oct
Avianca Logo
3:10 p.m. - 11:00 p.m.PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
8h 50m1 stop Bogotá El Dorado
Avianca Logo
4:55 a.m. - 5:00 p.m.MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
11h 05m1 stop Bogotá El Dorado
C$ 510Avianca
Thu, 24 Dec - Wed, 30 Dec
Copa Airlines Logo
11:44 a.m. - 2:30 p.m.PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
3h 46mdirect
Copa Airlines Logo
3:30 p.m. - 8:20 p.m.MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
3h 50mdirect
C$ 523Copa Airlines
Sun, 24 Jan - Sun, 31 Jan
Copa Airlines Logo
11:44 a.m. - 2:30 p.m.PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
3h 46mdirect
Copa Airlines Logo
9:10 a.m. - 1:54 p.m.MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
3h 44mdirect
C$ 538Copa Airlines
Wed, 4 Nov - Wed, 11 Nov
Copa Airlines Logo
7:20 p.m. - 10:05 p.m.PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
3h 45mdirect
Copa Airlines Logo
5:55 a.m. - 10:47 a.m.MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
3h 52mdirect
C$ 554Copa Airlines
Tue, 13 Oct - Sat, 17 Oct
Avianca Logo
10:10 a.m. - 11:00 p.m.PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
13h 50m1 stop Bogotá El Dorado
Avianca Logo
12:40 a.m. - 9:15 a.m.MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
7h 35m1 stop Bogotá El Dorado
C$ 566Avianca
Fri, 23 Oct - Sun, 25 Oct
Avianca Logo
5:30 a.m. - 10:55 a.m.PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
6h 25m1 stop San Salvador El Salvador Intl
Avianca Logo
11:20 p.m. - 9:10 a.m.MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
8h 50m1 stop Bogotá El Dorado
C$ 568Avianca
Tue, 13 Oct - Sun, 18 Oct
Aeromexico Logo
3:05 p.m. - 6:00 p.m.PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
3h 55mdirect
Aeromexico Logo
9:05 a.m. - 1:55 p.m.MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
3h 50mdirect
C$ 576Aeromexico
Thu, 1 Oct - Thu, 15 Oct
Avianca Logo
3:10 p.m. - 11:00 p.m.PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
8h 50m1 stop Bogotá El Dorado
Avianca Logo
11:20 p.m. - 9:15 a.m.MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
8h 55m1 stop Bogotá El Dorado
C$ 583Avianca
Tue, 6 Oct - Tue, 13 Oct
Copa Airlines Logo
7:12 p.m. - 10:05 p.m.PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
3h 53mdirect
Copa Airlines Logo
3:30 p.m. - 8:14 p.m.MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
3h 44mdirect
C$ 593Copa Airlines
Booking Insights

Price, demand, and travel trends for Panama City to Mexico City flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights from Panama City to Mexico City with more confidence.

How much is a round-trip flight from Panama City to Mexico City?

Round-trip flights from Panama City to Mexico City start at C$ 509. Prices are typical for this route right now, with typical round-trip fares ranging from C$ 486 to C$ 708. The lowest price found in the past 5 days was C$ 509 on Avianca.

What's the cheapest day of the week to fly from Panama City to Mexico City?

Wednesday is the cheapest day of the week to fly from Panama City to Mexico City and is 4% cheaper than the average day. Saturday is the most expensive day with flight prices 12% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Panama City to Mexico City?

•February is the cheapest month to fly from Panama City to Mexico City at C$ 491 round-trip.
•October (C$ 679) and June (C$ 655) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 38% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Panama City to Mexico City the cheapest?

Flights from Panama City to Mexico City are cheapest 12 weeks before departure. Booking in this window typically costs about 19% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Expert advice

Expert advice for your flight from Panama City to Mexico City

 
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on MEX

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Key details for Panama City to Mexico City flights

Low season

August

Cheapest flight

C$ 282
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly (1% more expensive on average)
Flights from Panama City to Mexico City

When to book flights from Panama City to Mexico City

Are your dates flexible? Find out the best times to travel from Panama City to Mexico City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Panama City to Mexico City flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines, and booking questions.

  • Are there onsite hotels at Mexico City Benito Juarez Airport?

    Courtyard by Marriott Mexico City Airport is within walking distance of the airport. You can book a room and rest if you arrive at night or experience flight delays. Apart from beds, you can enjoy other amenities, including entertainment, meals, drinks, and a shower.

  • How can I travel from downtown Panama City to Panama City Tocumen International Airport?

    The quickest way to get to the airport is by taking a taxi. However, you can take a bus from Albrook Bus Terminal. You can also take a train at Metro de Panama if you prefer public transport.

  • Which is the most sustainable flight from Panama City to Mexico City?

    Copa Airlines use sustainable aviation fuel to reduce the impact of carbon on the environment. These airlines ensure a greener environment by upgrading fleets since 2000 and using RNAV satellite navigation for fuel conservation. Furthermore, these airlines ensure efficiency by optimizing taking off and landing, speed and attitude, convenient flight scheduling, and maintaining the planes. In addition, it has a recycling program and uses biodegradable products to improve environmental cleanliness.

  • Is there public transport to downtown Mexico City from MEX airport?

    You can take a train at line 5 subway that takes 39 minutes, a line 4 bus that takes about 52min, or a shuttle that takes about 50 minutes to get to the city. You can take the night bus at line 1 subway, about 38 minutes to the city if you're traveling late.

  • Which airlines offer extra legroom and free seat selection on Panama City to Mexico City flights?

    Among airlines operating Panama City to Mexico City flights:

    • Copa Airlines: offers extra legroom; offers free seat selection
    • Aeromexico: offers extra legroom; offers free seat selection

    Extra legroom and free seat selection availability depends on fare class and route.

  • Which airlines are available on the route from Panama City to Mexico City?

    2 airlines operate flights between Panama City and Mexico City. The airlines offering direct flights on this route include:

    • Copa Airlines
    • Aeromexico

  • Which airports can I use when flying from Panama City to Mexico City?

    Flights from Panama City to Mexico City usually depart from Panama City Tocumen Intl (PTY) and arrive at Mexico City Benito Juarez (MEX).

  • Which airlines include bags at no extra cost on Panama City to Mexico City flights?

    Here are some options for this route, based on selected ticket types and cabin classes:

    • Copa Airlines: a carry-on bag and a checked bag in Economy Class
    • Aeromexico: a carry-on bag and a checked bag in Economy Class
    • AeroMexico Connect: a cabin bag in Economy Class class

    Bag allowance can vary by ticket type, cabin class, route, and airline, so travellers should check the fare details before booking.

  • Which cabin classes can I book on flights from Panama City to Mexico City?

    Only Economy Class is available on flights from Panama City to Mexico City.

  • How much can I save by taking a layover when flying from Panama City to Mexico City?

    On this route, direct and layover fares are close on average, with direct at C$ 558 round-trip and layover options via Bogotá El Dorado (BOG) at C$ 549.

  • What is the standard checked bag allowance on flights from Panama City to Mexico City?

    There is no standard. Checked bag policies vary by airline on this route. Most carriers charge C$ 84–C$ 139 for the first checked bag in economy. Premium fares and elite status bookings typically include a free checked bag.

  • Which aircraft model is used most often on flights from Panama City to Mexico City?

    The Boeing 737-800 family is used most often on this route, operated mainly by Copa Airlines. Other aircraft seen on the route include Embraer 190 variants.

  • Which airports do connecting flights from Panama City to Mexico City pass through?

    One-stop flights from Panama City to Mexico City most commonly connect through:

    • Bogotá El Dorado (BOG) – 58% of one-stop connections
    • San Salvador El Salvador Intl (SAL) – 42% of one-stop connections
    • Cancun (CUN) – 0% of one-stop connections
    • Guatemala City La Aurora (GUA) – 0% of one-stop connections

    Bogotá El Dorado (BOG) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Panama City to Mexico City?

    Yes. Being flexible with your travel dates can save you up to 14% on the Panama City to Mexico City route. Wednesday is the cheapest departure day at C$ 537 round-trip on average, while Saturday is the most expensive at C$ 622, a difference of C$ 85. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • At what point is a flight considered delayed on the route from Panama City to Mexico City?

    A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Panama City to Mexico City route, 4% of flights were delayed in the past 3 months, with delays averaging 2 hours 30 minutes.

  • How are flight departures from Panama City to Mexico City spread across the day?

    Morning is the busiest departure period on Panama City to Mexico City flights, with 29% leaving in that window. Afternoon departures account for 29%, Evening flights for 28%, and Night flights for 14%.

  • Which popular places can I visit in Mexico City?

    Some of the most popular sights in Mexico City are Parque España, Palacio de los Deportes, and El Ángel de la Independencia. These are among the most viewed places in Mexico City on KAYAK.

  • What are the earliest and latest flights from Panama City to Mexico City?

    These are the earliest and latest flight times available from Panama City to Mexico City:

    • Earliest: departs at 9:19 am and lands at 1:09 pm
    • Latest: departs at 10:17 pm and lands at 2:07 am.

    The flight takes about 3h 50m.

  • How expensive are last-minute Panama City to Mexico City flights?

    Last-minute fares on this route – booked within 2 weeks of departure – run 7% above the route average of C$ 553. Book 12 weeks before departure for the lowest fares.

  • How long does a flight from Panama City to Mexico City take?

    A direct flight from Panama City to Mexico City takes 3h 50m, covering 3,878 km.

  • Do I need a passport to fly from Panama City to Mexico City?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Panama City to Mexico City changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about C$ 509 to C$ 1,414. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Panama City to Mexico City looking right now?

    One-way fares from Panama City to Mexico City are currently in line with typical prices for this route. Average one-way fares are about C$ 376.

  • How does Copa Airlines's on-time performance compare to other airlines on Panama City to Mexico City flights?

    Copa Airlines is slightly above the route average for timely arrivals, while AeroMexico Connect has a lower on-time arrival rate. On-time arrival rates on Panama City to Mexico City flights are:

    • Copa Airlines: 97% on time
    • AeroMexico Connect: 94% on time
    • Aeromexico: 93% on time

    On average, flights on this route are punctual 96% of the time.

  • How do delay rates compare for morning and evening flights from Panama City to Mexico City?

    Morning flights have the fewest delays on this route. Delays tend to pile up throughout the day as one late flight pushes the next, so earlier departures are usually more reliable.

  • How much time can I save by choosing a different layover airport when travelling from Panama City to Mexico City?

    Flying via San Salvador El Salvador Intl (SAL) gives the shortest average 1-stop total travel time at 7h 21m, compared with 9h 24m via Bogotá El Dorado (BOG) and 9h 56m via Cancun (CUN).

  • What is the time difference between Panama City and Mexico City?

    Mexico City is 1 hour behind Panama City (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Mexico City Benito Juarez Airport (MEX)?

    Mexico City Benito Juarez Airport (MEX) hosts 5 major car rental companies, with daily rates starting from around C$ 2 for economy cars. Top options include:
    • Budget
    • Infinity Car Rental
    • Europcar
    • MEXRENTACAR
    • America Car Rental

  • How much should I expect to pay for a Panama City to Mexico City flight?

    Round-trip flights from Panama City to Mexico City range from C$ 486 to C$ 708, with an average of C$ 553 over the past 12 months. Anything below C$ 486 counts as a good deal.

Your guide to booking Panama City to Mexico City flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure instead of Saturday. On this route, Wednesday flights average C$ 537 – about C$ 85 less than Saturday (14% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 12 weeks before you fly. On this route, that window historically saves about 19% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Panama City to Mexico City trip for February. Fares historically average C$ 491 round-trip in that month – typically C$ 188 less than the most expensive month, which is October (based on the last 12 months).
  • If arriving on time is high on your priority list, Copa Airlines is the strongest pick on this route. 97% of Copa Airlines flights from Panama City to Mexico City arrived on time in the past 3 months, slightly above the route's average on-time arrival rate of 96%. When flights on this route do arrive late, the average delay is 2 hours30 minutes, so choosing a carrier with strong on-time performance can make a difference on tight schedules.
  • If you have the time, taking a 1-stop flight through Bogotá El Dorado Airport (BOG) can be cheaper than flying direct. The cheapest layover option averages C$ 549 round-trip on this route – about C$ 10 less than direct flights (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Mexico City Benito Juarez Airport.
    - Camino Real Aeropuerto Mexico
    - NH Collection Mexico City Airport T2
    - Courtyard by Marriott Mexico City Airport
  • If you need to relax, enjoy a meal, or drink before your flight, you can rest at Panama City Tocumen International airport (PTY) lounges. If you're flying economy, you need to pay at the door, buy an annual pass, or purchase a day pass. The lounges include Tocumen Royal Saloon on the 3rd Floor, Copa Club on the 2nd floor, and The Lounge Panama near Gate 115.
  • Panama City Tocumen International Airport offers convenient car parking areas near the airport’s Main Terminal T1 and South Terminal T2. Alternatively, you can park your car on the off-site parking sites that are pocket-friendly and offer you a ride to your convenient airport terminal.
  • Mexico City Benito Juarez Airport (MEX) is a hub for Aeromexico, Volaris, and Aeromar. It also serves domestic and international flights. At the same time, Panama City Tocumen International Airport is a regional hub between North America, the Caribbean, and South America and a base for Copa Airlines.
  • There are car rentals available near Terminals 1 and 2 at Mexico City Benito Juarez Airport. You can choose a car you prefer from several car rentals, including Dollar, National, and E-Z Rent-A-Car. A valid driver's license is the most needed document when renting a car. However, you must be at least 21 years old to rent a vehicle.
  • When choosing flights from Panama City to Mexico City, you can book Copa Airlines if you need in-flight entertainment. You can enjoy music in various languages, including English, Spanish, and Portuguese. Again, you can enjoy your own entertainment through Copa Showpass.

Prefer to fly direct from Panama City to Mexico City?

 
Find which airlines fly direct from Panama City Tocumen Intl Airport to Mexico City Benito Juarez Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Mexico City Benito Juarez

Monday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Tuesday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Wednesday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Thursday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Friday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Saturday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Sunday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

See more nonstop flights

Direct returns

Mexico City Benito Juarez to Panama City Tocumen Intl

Monday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Tuesday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Wednesday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Thursday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Friday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Saturday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Sunday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

See more nonstop flights

More options for your flight from Panama City to Mexico City

Complete your trip to Mexico City with a hotel stay or car rental